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Phenotypes Associated with This Genotype
Genotype
MGI:3046889
Allelic
Composition		 Igf1sl1C3H/HeJ/Igf1sl1C3H/HeJ
Genetic
Background		 involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating insulin-like growth factor I level ( J:66640 , J:94512 )
• decreased serum IGF-1 levels (J:94512)

skeleton
decreased bone mineral density of lumbar vertebrae ( J:94512 )
• reduced trabecular and cortical bone mineral density of the L5 vertebrae
decreased bone ossification ( J:94512 )
• reduced rate of bone formation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory