behavior/neurological
N |
• homozygotes exhibit normal spatial learning (water-maze test)
• homozygotes show normal motor coordination (rota-rod test)
• consistent with grossly normal hippocampal functions, acquisition and performance levels are only slightly, but insignificantly, reduced in the two-way active-avoidance paradigm
• other behavioral paradigms indicate normal gross sensory functions, reflexes, home cage activity, and food consumption
|