Phenotypes Associated with This Genotype

Genotype
MGI:3046064

• Allelic Composition: Hoxb4^tm1.1Karl/Hoxb4^tm1.1Karl
• Genetic Background: involves: 129 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal definitive hematopoiesis ( J:90976 )

• the proliferative response of primitive hematopoietic progenitor cells is decreased

decreased bone marrow cell number ( J:90976 )

• a significant decrease in bone marrow cellularity is seen

decreased erythrocyte cell number ( J:90976 )

• a small but significant decrease in red blood cell count is seen

decreased hemoglobin content ( J:90976 )

• a small but significant decrease in hemoglobin content is seen

spleen hypoplasia ( J:90976 )

• a significant decrease in the cellularity of the spleen is seen

immune system

spleen hypoplasia ( J:90976 )

• a significant decrease in the cellularity of the spleen is seen