Phenotypes Associated with This Genotype

Genotype
MGI:3045953

• Allelic Composition: Kit^tm2Ber/Kit⁺
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:89602 )

• ~10% died during the neonatal period

• most heterozygotes survived for at least 1 year

pigmentation

absent coat pigmentation ( J:89602 )

• in regions where the coat was white, melanin pigment was absent from the hair shafts and melanocytes were absent from the hair bulbs

white spotting ( J:89602 )

variable depigmentation ( J:89602 )

• observed in 2% to 5% of mice

• >90% of the body surface area white except around the ear

reproductive system

reproductive system phenotype ( J:89602 )

N • mice were fully fertile

integument

absent coat pigmentation ( J:89602 )

• in regions where the coat was white, melanin pigment was absent from the hair shafts and melanocytes were absent from the hair bulbs

white spotting ( J:89602 )

variable depigmentation ( J:89602 )

• observed in 2% to 5% of mice

• >90% of the body surface area white except around the ear