Analysis Tools
mortality/aging
|
• ~20% died within 12 hours of birth
• surviving mice lived for at least 1 year
|
pigmentation
|
• in regions where the coat was white, melanin pigment was absent from the hair shafts and melanocytes were absent from the hair bulbs
|
|
• observed in 10% to 15% of mice
• >90% of the body surface area white except around the ear
|
digestive/alimentary system
| N |
• neither stomach or intestinal distension were observed as was in Kittm3Ber/tm3Ber mice
|
hematopoietic system
|
• reduced number of mast cells in the peritoneal cavity, and the stomach
• normal number of mast cell precursor cells and it was possible to derive mast cells from the bone marrow
|
immune system
| N |
• splenomegaly was not observed, as it was in Kittm3Ber/tm3Ber mice
|
|
• reduced number of mast cells in the peritoneal cavity, and the stomach
• normal number of mast cell precursor cells and it was possible to derive mast cells from the bone marrow
|
reproductive system
| N |
• mice were fully fertile
|
integument
|
• in regions where the coat was white, melanin pigment was absent from the hair shafts and melanocytes were absent from the hair bulbs
|
|
• observed in 10% to 15% of mice
• >90% of the body surface area white except around the ear
|
