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Phenotypes Associated with This Genotype
Genotype
MGI:3045436
Allelic
Composition		 Btlatm1Kay/Btlatm1Kay
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Btlatm1Kay mutation (1 available); any Btla mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell activation ( J:89864 )
• lymph node T cells are hyper-responsive to T cell receptor mediated activation
• peripheral lymphoid organ cell subpopulations are otherwise normal

hematopoietic system
abnormal T cell activation ( J:89864 )
• lymph node T cells are hyper-responsive to T cell receptor mediated activation
• peripheral lymphoid organ cell subpopulations are otherwise normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory