Phenotypes Associated with This Genotype

Genotype
MGI:3045412

• Allelic Composition: Ctnnb1^tm2Kem/Ctnnb1^tm2Kem; Tg(Col2a1-cre)1Bhr/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial bone morphology ( J:90567 )

domed cranium ( J:90567 )

limbs/digits/tail

short limbs ( J:90567 )

skeleton

abnormal craniofacial bone morphology ( J:90567 )

domed cranium ( J:90567 )

decreased length of long bones ( J:90567 )

• endochondral bone elements all shorter

abnormal cartilage morphology ( J:90567 )

abnormal chondrocyte morphology ( J:90567 )

• chondrocyte morphology reduced about 34%