Phenotypes Associated with This Genotype

Genotype
MGI:3045115

• Allelic Composition: Kitl^Sl-con/Kitl^Sl-con
• Genetic Background: either: (involves: C3H/HeJ) or (involves: C3H/HeN)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:23593 )

• uniformly gray coat

abnormal skin pigmentation ( J:23593 )

hyperpigmentation ( J:23593 )

• hyperpigmentation of the genitals

• occasional abnormal pigmentation of regions of the oviduct due to the accumulation of melanocytes

endocrine/exocrine glands

impaired ovarian folliculogenesis ( J:23593 )

♀ • follicular development is initially delayed, and although follicular development is relatively normal around 4 weeks of age, follicles fail to be maintained after 5 weeks of age

hematopoietic system

increased mast cell number ( J:23593 )

• accumulation of mast cells in the reproductive tract, with the highest degree of accumulation in the serosal membrane

immune system

increased mast cell number ( J:23593 )

• accumulation of mast cells in the reproductive tract, with the highest degree of accumulation in the serosal membrane

reproductive system

reproductive system phenotype ( J:23593 )

N • no defects were observed in the postnatal testes

decreased oocyte number ( J:23593 )

♀

impaired ovarian folliculogenesis ( J:23593 )

♀ • follicular development is initially delayed, and although follicular development is relatively normal around 4 weeks of age, follicles fail to be maintained after 5 weeks of age

integument

abnormal coat/hair pigmentation ( J:23593 )

• uniformly gray coat

abnormal skin pigmentation ( J:23593 )

cellular

decreased oocyte number ( J:23593 )

♀