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Phenotypes Associated with This Genotype
Genotype
MGI:3044052
Allelic
Composition		 Idd10NOD/ShiLt/Idd10NOD/ShiLt
Idd3NOD/Idd3NOD
Genetic
Background		 B6.NOD-Idd3NOD Idd10NOD/Lt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd10NOD/ShiLt mutation (2 available); any Idd10 mutation (10 available)
Idd3NOD mutation (2 available); any Idd3 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal NK T cell physiology ( J:85823 )
• decreased cytokine response of iNKT cells when stimulated with antigens
abnormal cytokine secretion ( J:85823 )
• decreased cytokine response (IL-2, IL-4, IFN-gamma, CSF-1) of iNKT cells when stimulated with antigens

hematopoietic system
abnormal NK T cell physiology ( J:85823 )
• decreased cytokine response of iNKT cells when stimulated with antigens

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory