Analysis Tools
skeleton
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• while basal osteoclastogenesis was normal, osteoclastogenesis was impaired relative to controls in response to an osteoclastogenic stimulus (the calcitropic hormone PTHrP)
• bone marrow-derived macrophages do not exhibit a robust osteoclastogenic response to M-CSF and RANK-L as seen in wild-type cells
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• in response to an osteoclastogenic stimulus, PTHrP, mutants exhibit fewer osteoclasts
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immune system
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• while basal osteoclastogenesis was normal, osteoclastogenesis was impaired relative to controls in response to an osteoclastogenic stimulus (the calcitropic hormone PTHrP)
• bone marrow-derived macrophages do not exhibit a robust osteoclastogenic response to M-CSF and RANK-L as seen in wild-type cells
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• in response to an osteoclastogenic stimulus, PTHrP, mutants exhibit fewer osteoclasts
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• IL-6 production in response to PTHrP injection is reduced in mutants
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hematopoietic system
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• while basal osteoclastogenesis was normal, osteoclastogenesis was impaired relative to controls in response to an osteoclastogenic stimulus (the calcitropic hormone PTHrP)
• bone marrow-derived macrophages do not exhibit a robust osteoclastogenic response to M-CSF and RANK-L as seen in wild-type cells
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• in response to an osteoclastogenic stimulus, PTHrP, mutants exhibit fewer osteoclasts
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cellular
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• while basal osteoclastogenesis was normal, osteoclastogenesis was impaired relative to controls in response to an osteoclastogenic stimulus (the calcitropic hormone PTHrP)
• bone marrow-derived macrophages do not exhibit a robust osteoclastogenic response to M-CSF and RANK-L as seen in wild-type cells
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