Phenotypes for Robo1 Robo3 MGI:3043207 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Robo1^tm1Matl/Robo1^tm1Matl Robo3^tm1Matl/Robo3^tm1Matl
Genetic Background	involves: 129/Sv * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo1^tm1Matl mutation (2 available); any Robo1 mutation (88 available)
Robo3^tm1Matl mutation (1 available); any Robo3 mutation (76 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal axon guidance ( J:89438 )

• at E11.5 embryos show significant midline crossing although some still fail to cross indicating a partial suppression of the Robo3^tm1Matl homozygous phenotype

cellular

abnormal axon guidance ( J:89438 )

• at E11.5 embryos show significant midline crossing although some still fail to cross indicating a partial suppression of the Robo3^tm1Matl homozygous phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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