Phenotypes for Robo3 Slit1 Slit2 MGI:3043203 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Robo3^tm1Matl/Robo3^tm1Matl Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2^tm1Matl
Genetic Background	involves: 129/Sv * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo3^tm1Matl mutation (1 available); any Robo3 mutation (71 available)
Slit1^tm1.1Matl mutation (0 available); any Slit1 mutation (70 available)
Slit2^tm1Matl mutation (2 available); any Slit2 mutation (88 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal axon guidance ( J:89438 )

• embryos show some midline crossing although the majority still fail to cross indicating a partial rescue of the Robo3^tm1Matl homozygous phenotype

cellular

abnormal axon guidance ( J:89438 )

• embryos show some midline crossing although the majority still fail to cross indicating a partial rescue of the Robo3^tm1Matl homozygous phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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