About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3043019
Allelic
Composition
Mobptm1Sak/Mobptm1Sak
Genetic
Background
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mobptm1Sak mutation (0 available); any Mobp mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• no gross behavioral anomalies

nervous system
• while the formation of compact myelin was normal, the radial component was abnormally straight (instead of zig-zag as in wild-type)
• in response to a dysmyelinating agent, hexachlorophene (HCP), there was an increased frequency of vacuolation relative to wild-type controls and a widening of the major dense lines which was not observed in wild-type controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory