Phenotypes Associated with This Genotype

Genotype
MGI:3042187

• Allelic Composition: Amhr2^tm1Bhr/Amhr2^tm1Bhr; Inha^tm1Bay/Inha^tm1Bay
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:36027 )

• multifocal Sertoli/granulosa cell tumors

increased granulosa cell tumor incidence ( J:36027 )

• multifocal granulosa cell tumors

increased testis tumor incidence ( J:36027 )

• testicular tumors, larger than those observed in Inha-deficient mice

increased Leydig cell tumor incidence ( J:36027 )

• Leydig cell neoplasia

reproductive system

increased granulosa cell tumor incidence ( J:36027 )

• multifocal granulosa cell tumors

increased testis tumor incidence ( J:36027 )

• testicular tumors, larger than those observed in Inha-deficient mice

increased Leydig cell tumor incidence ( J:36027 )

• Leydig cell neoplasia

dilated uterus ( J:36027 )

• the uteri observed in male pseudohermaphrodites were dilated and fluid-filled

male pseudohermaphroditism ( J:36027 )

secondary sex reversal ( J:36027 )

endocrine/exocrine glands

increased granulosa cell tumor incidence ( J:36027 )

• multifocal granulosa cell tumors

increased testis tumor incidence ( J:36027 )

• testicular tumors, larger than those observed in Inha-deficient mice

increased Leydig cell tumor incidence ( J:36027 )

• Leydig cell neoplasia