Analysis Tools
mortality/aging
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• obvious decline in survival between 450 and 600 days of age, whereas wild-type controls had no such decline
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neoplasm
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• at 20 months of age 80% of mice examined had tumors, incidence in wild-type controls was 30%
• at 20 months of age incidence of tumors in multiple organs was 37% vs. 4% in wild-type controls
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• at 20 months, in 3% of mice examined vs. 0% in wild-type controls
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• at 20 months, 3% of mice examined had fibrosing large cell lymphoma vs. 0% in wild-type controls
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• at 20 months of age 37% of mice examined had diffuse large B-cell lymphoma vs. 0% in wild-type controls
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• at 20 months, in 37% of mice examined vs. 17% in wild-type controls
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• at 20 months, 5% of mice examined had hemangiosarcoma vs. 0% in wild-type controls
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respiratory system
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• at 20 months, in 37% of mice examined vs. 17% in wild-type controls
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endocrine/exocrine glands
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• at 20 months, in 3% of mice examined vs. 0% in wild-type controls
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nervous system
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• at 20 months, in 3% of mice examined vs. 0% in wild-type controls
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