Phenotypes Associated with This Genotype

Genotype
MGI:3040867

• Allelic Composition: C3^tm1Pkna/C3^tm1Pkna
• Genetic Background: D1.129P2-C3^tm1Pkna

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased susceptibility to induced arthritis ( J:88872 )

• reduced penetrance of induced arthritis, with only 75% of mice developing inflammation

• reduced severity of induced arthritis relative to control mice

• delayed onset of induced arthritis relative to control mice

skeleton

decreased susceptibility to induced arthritis ( J:88872 )

• reduced penetrance of induced arthritis, with only 75% of mice developing inflammation

• reduced severity of induced arthritis relative to control mice

• delayed onset of induced arthritis relative to control mice