About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3040601
Allelic
Composition
Tcf12tm1Zhu/Tcf12+
Tcf4tm1Zhu/Tcf4+
Genetic
Background
involves: 129P2/OlaHsd * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf12tm1Zhu mutation (0 available); any Tcf12 mutation (64 available)
Tcf4tm1Zhu mutation (1 available); any Tcf4 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most homozygotes died within two weeks of birth

growth/size/body
• evident after birth

hematopoietic system
• 50% reduction in the number of pro-B cells

immune system
• 50% reduction in the number of pro-B cells

nervous system
N
• the pontine nucleus develops normally


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory