Phenotypes Associated with This Genotype

Genotype
MGI:3040597

• Allelic Composition: Tcf4^tm1Zhu/Tcf4^tm1Zhu
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:43324 )

• homozygotes born with low frequency and died within one week of birth

hematopoietic system

decreased pro-B cell number ( J:43324 )

• 50% reduction in the number of pro-B cells in homozygotes

immune system

decreased pro-B cell number ( J:43324 )

• 50% reduction in the number of pro-B cells in homozygotes