Mouse Genome Informatics
hm
    Selltm1Flv/Selltm1Flv
involves: C57BL/6 * NOD
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
endocrine/exocrine glands
• inflammation of the islet of Langerhans is seen by 9 weeks in mutant and wild-type mice

immune system
• inflammation of the islet of Langerhans is seen by 9 weeks in mutant and wild-type mice
• adoptive transfer experiment results with mutants backcrossed to NOD for 10 or more generations indicate that this reduction is a result of incomplete NOD genetic background
• the incidence of diabetes in these mutants is also decreased as a result of incomplete NOD genetic background

Mouse Models of Human Disease
OMIM IDRef(s)
Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:88974