Mouse Genome Informatics
hm
    GckRgsc392/GckRgsc392
involves: C57BL/6J * DBA/2J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
growth/size
• growth retardation is not as severe as in Gck1Rgsc and Gck6Rgsc

homeostasis/metabolism
• hyperglycemia is detected by P2
• blood glucose levels reach 500 mg/dl and remain this high for at least 3 weeks after birth
• histological analysis reveals reduced liver glycogen levels

liver/biliary system
• histological analysis reveals increased numbers of fat droplets in hepatocytes however the gross appearance on the liver does not differ from wild-type

Mouse Models of Human Disease
OMIM IDRef(s)
Maturity-Onset Diabetes of the Young, Type 2; MODY2 125851 J:88919