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Phenotypes Associated with This Genotype
Genotype
MGI:3038216
Allelic
Composition
GckRgsc341/Gck+
Genetic
Background
involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GckRgsc341 mutation (1 available); any Gck mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• increased glycosylated hemoglobin indicating a prolonged increase in serum glucose
• mutants have a free fed serum glucose level of 200 mg/dl or more, this was the basis for selection in the ENU screen
• during an oral glucose tolerance test blood glucose levels are significantly higher

hematopoietic system
• increased glycosylated hemoglobin indicating a prolonged increase in serum glucose


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory