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Phenotypes Associated with This Genotype
Genotype
MGI:3038110
Allelic
Composition		 Gata1tm1Mym/Y
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm1Mym mutation (0 available); any Gata1 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Gata1tm1Mym/Y embryos are smaller and anemic

mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:40321 )
• embryonic lethality is first detected at E11.5 and no live males seen by E12.5

hematopoietic system
abnormal embryonic erythropoiesis ( J:40321 )
• impaired primitive erythropoiesis
decreased erythroid progenitor cell number ( J:40321 )
• decrease in the number of erythroid cells and CFU-E in livers

embryo
absent vitelline blood vessels ( J:40321 )
• yolk sacs contain almost no blood vessels at E9.5
abnormal embryonic erythropoiesis ( J:40321 )
• impaired primitive erythropoiesis

growth/size/body
decreased embryo size ( J:40321 )

liver/biliary system

cardiovascular system
absent vitelline blood vessels ( J:40321 )
• yolk sacs contain almost no blood vessels at E9.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory