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Phenotypes Associated with This Genotype
Genotype
MGI:3037204
Allelic
Composition		 Srsf2tm1Xdfu/Srsf2+
Tg(Lck-cre)I57Jxm/?
Genetic
Background		 involves: 129S4/SvJae * 129X1/SvJ * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srsf2tm1Xdfu mutation (1 available); any Srsf2 mutation (13 available)
Tg(Lck-cre)I57Jxm mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased thymus weight ( J:88668 )
• a modest reduction in thymic weight is seen
decreased thymocyte number ( J:88668 )
• a modest reduction in the total number of thymocytes is seen

immune system
decreased thymus weight ( J:88668 )
• a modest reduction in thymic weight is seen
decreased thymocyte number ( J:88668 )
• a modest reduction in the total number of thymocytes is seen

endocrine/exocrine glands
decreased thymus weight ( J:88668 )
• a modest reduction in thymic weight is seen
decreased thymocyte number ( J:88668 )
• a modest reduction in the total number of thymocytes is seen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory