cellular
azoospermia
(
J:88035
)
|
• total lack of sperm in seminal fluid
|
|
• the most advanced germ cells present are spermatogonia and pachytene spermatocytes indicating male meiosis does not progress beyond prophase I
|
mortality/aging
• reduced numbers of double homozygotes are born
|
endocrine/exocrine glands
|
• large vacuolated structures and large multinucleated giant cells found in tubules
• large numbers of apoptotic cells in tubules of testes
|
small testis
(
J:88035
)
|
• less than 50% of wild-type
|
growth/size/body
• reduced by about 20% compared to wild-type
|
• reduced by about 20% compared to wild-type
|
reproductive system
|
• large vacuolated structures and large multinucleated giant cells found in tubules
• large numbers of apoptotic cells in tubules of testes
|
small testis
(
J:88035
)
|
• less than 50% of wild-type
|
azoospermia
(
J:88035
)
|
• total lack of sperm in seminal fluid
|
|
• the most advanced germ cells present are spermatogonia and pachytene spermatocytes indicating male meiosis does not progress beyond prophase I
|