Phenotypes for Gli2 MGI:3032763 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gli2^{tm5.1(GLI3)Alj}/Gli2^{tm5.1(GLI3)Alj}
Genetic Background	involves: Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli2^{tm5.1(GLI3)Alj} mutation (0 available); any Gli2 mutation (173 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:87948 )

• pups live for only 2 days after birth

nervous system

abnormal neuron specification ( J:87948 )

• abnormal spatial patterning of ventral spinal cord progenitors

• partial rescue of the spinal cord development phenotype observed in homozygous Gli2^tm1Alj mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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