Phenotypes Associated with This Genotype

Genotype
MGI:3032762

• Allelic Composition: Gli2^tm5(GLI3)Alj/Gli2^tm5(GLI3)Alj
• Genetic Background: involves: Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal floor plate morphology ( J:87948 )

• some floor plate cells form in the cervical and forelimb regions but not in the trunk and hindlimb regions

abnormal neuron specification ( J:87948 )

• abnormal spatial patterning of ventral spinal cord progenitors

• partial rescue (less than Gli2^{tm5.1(GLI3)Alj} homozygotes) of the spinal cord development phenotype observed in Gli2^tm1Alj homozygotes

abnormal ventral interneuron 3 morphology ( J:87948 )

• partial rescue of V3 interneuron generation

embryo

abnormal floor plate morphology ( J:87948 )

• some floor plate cells form in the cervical and forelimb regions but not in the trunk and hindlimb regions