Mouse Genome Informatics
hm
    Tgcog/Tgcog
involves: AKR/J * C57BL/6By
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
endocrine/exocrine glands
• hypertrophy of thyrofollicular cells

growth/size/body
• evident at day 15 postnatal (J:3079)
• evident by 15 days postnatal (J:8567)
• repaired when diet at weaning was supplemented with desiccated thyroid powder (J:8567)

hematopoietic system

homeostasis/metabolism

nervous system
• cerebrum and cerebellum weighed significantly less than littermate controls
• brain stem weight equivalent to littermate controls
• hypomyelination, restricted to cerebrum

Mouse Models of Human Disease
OMIM IDRef(s)
Thyroid Dyshormonogenesis 3; TDH3 274700 J:8567