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Phenotypes Associated with This Genotype
Genotype
MGI:3029986
Allelic
Composition		 Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1tm2(Runx1)Toku mutation (0 available); any Runx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell subpopulation ratio ( J:87697 )
• lower CD4/CD8 cell ratio of splenic T lymphocytes

immune system
abnormal T cell subpopulation ratio ( J:87697 )
• lower CD4/CD8 cell ratio of splenic T lymphocytes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory