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Phenotypes Associated with This Genotype
Genotype
MGI:3029468
Allelic
Composition
Sox8tm1Weg/Sox8tm1Weg
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox8tm1Weg mutation (0 available); any Sox8 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• smaller adipose stores

growth/size/body
• adult homozygous mice weigh approximately 30% less than controls

limbs/digits/tail
• reduced size of several tarsals was noted by P7; small size precludes the ability of tarsals to fuse in the adult

skeleton
• reduced size of several tarsals was noted by P7; small size precludes the ability of tarsals to fuse in the adult


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory