Mouse Genome Informatics
hm
    Tgm2tm1Gml/Tgm2tm1Gml
involves: 129X1/SvJ * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• increased death (~60% of treated mice died) after carbon tetrachloride (CCl4) administration

hematopoietic system
• small, but significant
• small, but significant

homeostasis/metabolism
• in fed, but not fasted, state
• after intraperitoneal glucose administration
• glucose intolerance after intraperitoneal glucose administration
• greater hypoglyemic response than controls upon intraperitoneal insulin administration
• in those that survived, increased hepatic injury after CCl4 administration

Mouse Models of Human Disease
OMIM IDRef(s)
Maturity-Onset Diabetes of the Young; MODY 606391 J:75566 , J:78633 , J:82489