Phenotypes for Mdm2 Trp53 MGI:3028928 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mdm2^tm1Bay/Mdm2^tm1Bay Trp53^tm1Snj/Trp53^tm1Snj
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mdm2^tm1Bay mutation (1 available); any Mdm2 mutation (53 available)
Trp53^tm1Snj mutation (1 available); any Trp53 mutation (249 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:87687 )

• failed to rescue embryonic lethality due to the homozygous Mdm2^tm1Bay condition

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24