Phenotypes Associated with This Genotype

Genotype
MGI:3028898

• Allelic Composition: Pou2f1^tm1Shrp/Pou2f1⁺; Pou2f2^tm1Bal/Pou2f2⁺
• Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:87664 )

• many transheterozygous mutants die within 24 hours of birth

postnatal lethality, incomplete penetrance ( J:87664 )

• a subset of mutants surviving birth die prior to weaning

behavior/neurological

lethargy ( J:87664 )

• surviving neonates become increasingly lethargic and runted

growth/size/body

decreased body weight ( J:87664 )

• surviving neonates have lower body weights