Phenotypes Associated with This Genotype

Genotype
MGI:3028767

• Allelic Composition: Rbl1^tm1Tyj/Rbl1^tm1Tyj
• Genetic Background: involves: 129S2/SvPas * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:34058 )

• homozygotes are viable, fertile, and display no developmental or pathological defects at 4-12 months of age

• neither tumors nor increased morbidity or mortality are observed up to 24 months of age

cellular

cellular phenotype ( J:34058 )

N • mutant embryonic fibroblasts (passage 4-6) derived from 12.5-day-old homozygotes exhibit normal cell cycle characteristics relative to wild-type cells

integument

integument phenotype ( J:82802 )

N • newborn homozygotes display normal epidermal terminal differentiation relative to heterozygous mutant littermates