Mouse Genome Informatics
hm
    Ercc4tm1Fwa/Ercc4tm1Fwa
involves: 129S6/SvEvTac
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice die approximately 3 weeks after birth

cellular
• abnormal hepatic cells with enlarged nuclei
• cultured embryonic fibroblasts were hypersensitive to UV irradiation and mitomycin C treatment

growth/size/body
• 73% decrease in body weight relative to wild-type and heterozygous littermates at 15 days of age

liver/biliary system

Mouse Models of Human Disease
OMIM IDRef(s)
Xeroderma Pigmentosum, Complementation Group F; XPF 278760 J:87684