Phenotypes for Ift88 MGI:3027344 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ift88^fxo/Ift88^tm1Rpw
Genetic Background	involves: 129/Sv * C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift88^fxo mutation (1 available); any Ift88 mutation (48 available)
Ift88^tm1Rpw mutation (0 available); any Ift88 mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:86437 )

nervous system

abnormal floor plate morphology ( J:86437 )

• lack the ventral midline groove in the neural plate

abnormal cranial flexure morphology ( J:86437 )

• sharp angle to mesencephalic flexure at E9.5-E10.5

limbs/digits/tail

preaxial polydactyly ( J:86437 )

• preaxial polydactyly

embryo

embryonic growth arrest ( J:86437 )

• development is arrested at E12.5-E13.5

abnormal floor plate morphology ( J:86437 )

• lack the ventral midline groove in the neural plate

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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