Phenotypes Associated with This Genotype

Genotype
MGI:3026630

• Allelic Composition: Frem1^crf11/Frem1^crf11
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:85113 )

• variable defects were noted

vision/eye

microphthalmia ( J:85113 , J:200175 )

cryptophthalmos ( J:200175 )

• high incidence of unilateral and bilateral cryptophthalmos

renal/urinary system

single kidney ( J:200175 )

• unilateral renal agenesis in 6.9% of affected animals

digestive/alimentary system

rectal prolapse ( J:200175 )

• propensity to develop rectal prolapse in adulthood

respiratory system

fused right lung lobes ( J:200175 )

• the cranial, medial, and caudal lobes of the right lung are partially or completely fused in 13/58 of affected mice