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Phenotypes Associated with This Genotype
Genotype
MGI:2684589
Allelic
Composition		 Hcn4tm1Jsr/Hcn4tm1Jsr
Myl2tm1(cre)Krc/Myl2+
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hcn4tm1Jsr mutation (0 available); any Hcn4 mutation (65 available)
Myl2tm1(cre)Krc mutation (2 available); any Myl2 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:86988 )
• homozygous embryos die between E9.5 and E11.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory