Phenotypes Associated with This Genotype

Genotype
MGI:2682830

• Allelic Composition: Esrra^tm1Vgi/Esrra^tm1Vgi
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased susceptibility to diet-induced obesity ( J:86433 )

• when 10-wk-old homozygotes are fed a high-fat diet for 5 weeks, they exhibit a significant reduction in weight gain % in the third week of feeding, and weigh only slightly more than wild-type mice fed a normal diet at the end of 5 weeks

homeostasis/metabolism

decreased susceptibility to diet-induced obesity ( J:86433 )

• when 10-wk-old homozygotes are fed a high-fat diet for 5 weeks, they exhibit a significant reduction in weight gain % in the third week of feeding, and weigh only slightly more than wild-type mice fed a normal diet at the end of 5 weeks