Phenotypes Associated with This Genotype

Genotype
MGI:2682214

• Allelic Composition: Gna11^Mhdadsk7/Gna11⁺
• Genetic Background: C3HeB/FeJ-Gna11^Mhdadsk7/Ieg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

hyperpigmentation ( J:81301 )

• excess pigmentation is also seen in the dermis of hair-bearing skin

• excess pigmentation is first seen at P3 increases through weaning then fades slightly with age

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

hearing/vestibular/ear

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

limbs/digits/tail

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

craniofacial

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

integument

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

growth/size/body

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals