Mouse Genome Informatics
hm
    Abcd1tm1Kds/Abcd1tm1Kds
involves: 129/Sv * 129S4/SvJae * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• evident between 15 and 20 months of age (J:75388)
• on rotarod test, evident between 15 and 20 months of age (J:75388)
• reduced rearing, evident between 15 and 20 months of age (J:75388)

nervous system
• evident at 16 months of age, enlarged processes contained myelin-like figures (J:75388)
• evident at 16 months of age, in CNS (J:75388)
• evident at 16 months of age, in CNS, white matter had redundant sheaths that failed to contact axons and in PNS, focal hypermyelination of sciatic nerves (J:75388)
• evident at 15 months of age, increased latency of compound muscle action potential (J:75388)

Mouse Models of Human Disease
OMIM IDRef(s)
Adrenoleukodystrophy; ALD 300100 J:75388