Analysis Tools
mortality/aging
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• a rapid decline in health is observed by the end of the fourth postnatal week and mice die within 3 days of overt signs of stress including reduced locomotion, round pupils, and reduced weight gain
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behavior/neurological
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• lack of locomotion is observed as health declines
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• some mice exhibit overt epilepsy within several days prior to death; typical seizures start with rearing adn loss of postural control, followed by running fits and violent convulsions
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nervous system
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• some mice exhibit overt epilepsy within several days prior to death; typical seizures start with rearing adn loss of postural control, followed by running fits and violent convulsions
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