About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:2679510
Allelic
Composition
Hba-a1tm1Ywk/Hba-a1+
Genetic
Background
involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hba-a1tm1Ywk mutation (0 available); any Hba-a1 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• heterozygotes are borderline anemic relative to wild-type controls
• however, heterozygotes are not hemolytic, as shown by normal reticulocyte counts
• heterozygotes display a borderline reduction in MCV, similar to that sometimes seen in human silent carriers, indicating a mild alpha-thalassemia phenotype


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/19/2026
MGI 6.24
The Jackson Laboratory