Mouse Genome Informatics
ht
    Hba-a1tm1Ywk/Hba-a1+
involves: 129X1/SvJ * C57BL/6J
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• heterozygotes are borderline anemic relative to wild-type controls
• however, heterozygotes are not hemolytic, as shown by normal reticulocyte counts
• heterozygotes display a borderline reduction in MCV, similar to that sometimes seen in human silent carriers, indicating a mild alpha-thalassemia phenotype

Mouse Models of Human Disease
OMIM IDRef(s)
Hemoglobin--Alpha Locus 1; HBA1 141800 J:35018