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Phenotypes Associated with This Genotype
Genotype
MGI:2679156
Allelic
Composition		 Recql4tm1Furu/Recql4tm1Furu
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Recql4tm1Furu mutation (0 available); any Recql4 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:85891 )
• homozygotes die between E3.5 and E6.5

embryo
decreased inner cell mass proliferation ( J:85891 )
• homozygotes display a significant decrease in the growth rate of the inner cell mass
abnormal trophoblast giant cell morphology ( J:85891 )
• homozygotes display a significant decrease in the growth rate of trophoblast cells

cellular
decreased inner cell mass proliferation ( J:85891 )
• homozygotes display a significant decrease in the growth rate of the inner cell mass

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/22/2025
MGI 6.24 		The Jackson Laboratory