Mouse Genome Informatics
hm
    Slc7a11sut/Slc7a11sut
C3H/HeSnJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
pigmentation
• yellow hair pigment is reduced; black pigment is unaffected
• most easily seen with agouti especially in the juvenile coat
• on nonagouti some reduction in yellow pigment can be seen in the pinna hairs only

hematopoietic system
• platelet serotonin concentration is slightly reduced; no change in adenine nucleotide concentration

homeostasis/metabolism
• platelet serotonin concentration is slightly reduced; no change in adenine nucleotide concentration
• model for mild storage pool deficiency
• mutant mice have a 3.4 fold greater bleeding time compared to sib controls

integument
• yellow hair pigment is reduced; black pigment is unaffected
• most easily seen with agouti especially in the juvenile coat
• on nonagouti some reduction in yellow pigment can be seen in the pinna hairs only

Mouse Models of Human Disease
OMIM IDRef(s)
Storage Pool Platelet Disease 185050 J:31616