Phenotypes Associated with This Genotype

Genotype
MGI:2677556

• Allelic Composition: Pdpk1^tm1Mlw/Pdpk1^tm1.2Mlw
• Genetic Background: involves: BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:85894 )

• homozygotes born at 25% lower ratio than expected

growth/size/body

decreased body size ( J:85894 )

• males about 45-50% smaller at birth

• females about 35% smaller at birth

• kidney, pancreas, spleen, adrenal gland all 50% smaller in size

• due to smaller cells