Phenotypes Associated with This Genotype

Genotype
MGI:2677528

• Allelic Composition: Pdpk1^tm1Mlw/Pdpk1^tm1Mlw
• Genetic Background: involves: BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:85894 )

• homozygotes born at 5% lower ratio than expected

growth/size/body

decreased birth body size ( J:85894 )

• animals of both sexes about 30% smaller at birth

decreased body size ( J:85894 )

• animals of both sexes remain smaller throughout their adult life

decreased body weight ( J:85894 )

• in females, difference in weight remains ~30% at 6 months of age

• in males, difference in weight is increased to ~45% by 6 months of age