Phenotypes Associated with This Genotype

Genotype
MGI:2677215

• Allelic Composition: Col2a1^Dmm/Col2a1⁺
• Genetic Background: involves: 101 * C3H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:6582 )

• 25% greater risk of death before weaning than wild-type littermates

craniofacial

shortened head ( J:6582 )

• short, blunt head

growth/size/body

shortened head ( J:6582 )

• short, blunt head

abnormal postnatal growth/weight/body size ( J:6582 )

• broad rump

disproportionate dwarf ( J:6582 )

• not evident at birth, but apparent at 1 week after birth and progressive

limbs/digits/tail

short limbs ( J:6582 )

skeleton

abnormal long bone epiphysis morphology ( J:6582 )

• reduction in height of proliferative and hypertrophic zones, but normal organization