Phenotypes Associated with This Genotype

Genotype
MGI:2677145

• Allelic Composition: Gfap^tm1Mes/Gfap^tm1Mes
• Genetic Background: either: (involves: 129S7/SvEvBrd * 129X1/SvJ) or (involves: 129S7/SvEvBrd * C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal astrocyte morphology ( J:64290 )

enhanced long-term potentiation ( J:64290 )

homeostasis/metabolism

increased susceptibility to injury ( J:48767 )

• mutant mice are highly sensitive to traumatic cervical spinal cord injury, with the presence of subpial and white matter hemorrhages in the ventral and lateral regions of the cervical cord

cellular

abnormal astrocyte morphology ( J:64290 )