Mouse Genome Informatics
hm
    Gp1batm1Ware/Gp1batm1Ware
Not Specified
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Transmission electron microscopy of mature megakaryocytes from Gp1batm1Ware/Gp1batm1Ware mice

homeostasis/metabolism
• tail bleeding times greater than ten minutes as compared to 3 minutes for controls

hematopoietic system
• megakaryocytes lack "developing platelet fields"
• demarcating platelet membranes are either vacuolated or disordered
• giant platelets found in the peripheral blood

cellular
• megakaryocytes lack "developing platelet fields"
• demarcating platelet membranes are either vacuolated or disordered

Mouse Models of Human Disease
OMIM IDRef(s)
Bernard-Soulier Syndrome; BSS 231200 J:63389