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Phenotypes Associated with This Genotype
Genotype
MGI:2672029
Allelic
Composition
Gp1batm1Ware/Gp1batm1Ware
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gp1batm1Ware mutation (0 available); any Gp1ba mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Transmission electron microscopy of mature megakaryocytes from Gp1batm1Ware/Gp1batm1Ware mice

homeostasis/metabolism
• tail bleeding times greater than ten minutes as compared to 3 minutes for controls

hematopoietic system
• megakaryocytes lack "developing platelet fields"
• demarcating platelet membranes are either vacuolated or disordered
• giant platelets found in the peripheral blood

cellular
• megakaryocytes lack "developing platelet fields"
• demarcating platelet membranes are either vacuolated or disordered

Mouse Models of Human Disease
OMIM ID Ref(s)
Bernard-Soulier Syndrome; BSS 231200 J:63389


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory