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Phenotypes Associated with This Genotype
Genotype
MGI:2671954
Allelic
Composition		 Runx1tm1Spe/Runx1tm2Spe
Genetic
Background		 either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1tm1Spe mutation (1 available); any Runx1 mutation (34 available)
Runx1tm2Spe mutation (0 available); any Runx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal embryonic hematopoiesis ( J:56184 )
• absence of hematopoietic colonies in fetal livers, vitelline and umbilical arteries
• no fetal liver hematopoiesis
• no yolk sac hematopoiesis

embryo
abnormal embryonic hematopoiesis ( J:56184 )
• absence of hematopoietic colonies in fetal livers, vitelline and umbilical arteries
• no fetal liver hematopoiesis
• no yolk sac hematopoiesis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory